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6

t h

A n n u a l E u r o p e a n C o n f e r e n c e o n

Gastroenterology

Euro Gastro 2018

J u n e 1 9 - 2 0 , 2 0 1 8

P a r i s , F r a n c e

Page 26

Journal of Clinical Gastroenterology and Hepatology

ISSN 2575-7733

F

or the first time the concept of "early cancer" in Russia (in St. Petersburg)

was brought from Japan in 2005. The number of completed endoscopic

mucosal resection (EMR) from 2005 to 2010 amounted to about 130

procedures. At first, we were very cautious about the selection of patients. For

EMR, we selected patients with adenoma, with high grade neoplasia and within

the mucosal adenocarcinoma. 90 EMR procedures were performed in the large

intestine, 35 of them were EPMR (piecemeal resection) in neoplasms larger

than 2 cm in diameter. The number of relapses was 25%. All these patients

were re-performed EMR. The number of complications at 90 EMR in the colon

was 2 deferred perforations that required surgical treatment and one delayed

bleeding that occurred on the 7

th

day after EMR. In the stomach, we performed

40 EMR; the indications were the same and also the neuro-endocrine tumors.

There were only 2 complications of this perforation of the stomach wall

against the background of atrophic changes, these patients were operated

on. The size of the formations did not exceed 2 cm. Relapse was observed

in only one case, but we managed independently by re-EMR. Simultaneously

with the accumulation of experience and improvement of manual skills in

2008, the technique of endoscopic sub mucosal dissection (ESD) begins to

develop. By 2013, we performed 51 ESDs, 48 in the stomach and three in the

colon. For comparison, in 2008 there were only 3 ESDs per year and in 2013

about 20. Indications for ESD were adenocarcinoma with Sm1a invasion, low-

grade adenocarcinomas within the mucous to 2 cm in diameter. At the same

time there were only three relapses due to careful selection of patients, the

development of manual skills through the creation of training to achieve the

number of performed ESD and this to fairly good results of treatment.

Biography

V Malkov has graduated from the St. Petersburg Pediatric

Medical Academy in 2006. In 2007, he completed the internship

for general surgery at the First Pavlov Medical University

and received primary training in Endoscopy. He worked as

an Endoscopist Surgeon in the Leningrad Regional Hospital

from 2007 to 2013. Since 2013, he served as the Head of

the Department of Endoscopy in the clinic of high medical

technologies named after NI Pirogov. He is an Assistant of the

Department of Endoscopy of the North Western State Medical

Mechnikov University. He is a permanent expert of the training

center of the company Endo Stars (training on biomodels for

endoscopists). He has nine publications in Russian Medical

journals.

wladimir.malkow@gmail.com

Endoscopic submucosal dissection as a treatment for early cancer.

Our experience

V Malkov

1

, L Myaukina

2

and A Philin

2

1

Saint Petersburg University Clinic of High Medical Technologies, Russia

2

Leningrad Region Hospital, Russia

V Malkov et al., J Clin Gastroenterol Hepatol 2018, Volume: 2

DOI: 10.21767/2575-7733-C1-002