Abdur Rub

Abdur Rub

 Assistant Professor

 
Deptt of Biotechnology, Jamia Millia Islamia (A Central University)
 
Biography

 

Dr.Abdur Rub won many prestigious awards including :SERB-DST-2013 Young Scientist Award by Deptt. of Science and Technology, India, INSA Medal for Young Scientists –2012 by Indian National Science Academy, India,CSIR-SRF by Council of Scientific & Industrial Research (CSIR), India, 2007-2010.CSIR-JRF by Council of Scientific & Industrial Research (CSIR), India, 2005-2007,National Eligibility Test (NET) by University Grant Commission (UGC) India, 2004,Graduate Aptitude Test in Engineering (GATE), by IIT Delhi, India, 2004,National Merit Scholarship from UP Board Allahabad, India,1996-2001
 
Research/Teaching Experience:Assistant Professor in the Deptt. of Biotechnology, Jamia Millia Islamia (A Central University), New Delhi (Oct. 2011 to till date),Assistant Professor in the Deptt. of Toxicology at Hamdard University, New Delhi, Postdoc  Fellow  at Immune Disease Institute, Harvard University, Boston, USA  (April 2010 to Aug. 2010) Ph.D  from National Centre for Cell Science, Pune (2005 to 2010)
Junior Research Fellow at National Centre for Biological Sciences (NCBS-TIFR), Bangalore (2004-2005)
 
Research Interest

 Pathogens and their hosts have had a two-way chat for millions years. This interaction has led to several measure/counter-measure reactions by the host and pathogen. The host immune system has developed numerous ways to neutralize and get rid of them. In turn, pathogens have also developed mechanisms to alter and evade the host immune response. Leishmania, a protozoan parasite, clearly manipulates the host to alter the immune responses. Leishmania causes leishmaniasis which is endemic in 89 countries including India, with a total of 12 million people infected worldwide and 350 million people at risk of infection. The molecular mechanisms and consequences of host immune evasion by Leishmania are poorly defined. My laboratory is interested in defining these molecular mechanisms and interactions of immune evasion. We currently investigated Leishmania disrupts macrophage-membrane lipid raft and impairs p38-mitogen-activated protein kinase (p38MAPK)-mediated CD40 signaling but enhances extracellular signal-related kinase (Erk-1/2)-mediated signalling.

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