Genomic biomarkers are variants in the DNA code that alone or in combination are associated with disease susceptibility, disease expression, and disease outcome, including therapeutic responses. Single nucleotide polymorphisms (SNPs; DNA sequence variation when a single nucleotide in the genome sequence is altered) have been evaluated extensively in relation to CVD. The 2 classic complementary approaches used for relating genetic sequence variation to CVD risk are the linkage approach and the association strategy.
Related Journals of Genomic Biomarkers
Journal of Genomics, International Journal of Genomics, Journal of Genetics and Genomics, Journals International Genomic Medicine