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Antimacrobial Activity and Synthese Of Thiosemicarbazide Amino Acid Derives

10th Edition of International Conference on Structural Biology
March 15-16 2018 Barcelona, Spain

Yamina C

University of Mostaganem, Algeria

Posters & Accepted Abstracts: Biochem Mol biol J

Abstract:

The 5-(1,5diamino-pentyl)-1-amino-1H-1,3,4-triazole-2-thiol [1] and the 5-(1,5 diamino-pentyl)-4-amino-S-glucosyl-1,2,4triazole [2] derivatives form amino acid were synthesized. The synthetic intermediates, ester, hydrazid and and thiosemicarbazide derivates have show a significant tendency to form S-Nucleosides with sugar (glucose). A novel nucleoside from oxadiazol the derivative with glucose was synthesized and was detected by IR spectroscopy and NMR [3]. The antimicrobial activity for final and synthetic intermediates in vitro against the microorganisms: Echerichia coli, Pseudomonas aeruginosa, Staphylococus aureus and Salmonelle chiguer were examined and some products showed noticeable activity against the tested miroorganisms [4]. References: 1. Z. Khiati, A. A.Othmane. Chem. Sci Trans. 1 (2012) 185193. 2. Y. Datoussaid et al. S.AFR.J. Chem. (2012) 65. 3. J.E.Mangette, et al. Tetrahdron. 65 (2009) 9536-6541. 4. S.Benhammadi, et al. Asian J Chem. (2010) 5535-5542

Biography :

Yamina C has completed her PhD at the age of 32 years from Oran University, ALGERIA. She is the student of Mostaganem University, Algeria. She has one publication on journal of   European Chemical Bulletin “Synthesis and Antimacrobial Activity of Some New L-Lysine Glycoside Derivatives”.

Email:chergui.amina@yahoo.fr