Figure 4:Inhibitory effects of glucose on KCa channels. In this experiment, the membrane potential was maintained at 40 mV. In control, infrequent KCa channel activity was seen. The application of 1 mmol/L A23187 activated the KCa channels by increasing [Ca2+]i. The activated KCa channels were blocked by 10 mmol/L glucose and reactivated by 1 nmol/L staurosporine.