Figure 3. Homogenates from two different mouse pancreata, lysates of the pancreatic acini-derived cell line AR42J and pancreatic juice were screened for BACE1 enzymatic activity using a fluorimetric BACE1 activity assay.Two preparations were produced from all samples and were measured three times each. BACE1 activity was detectable in all samples. Measured activity is shown in units of specific activity per μg protein (mean± SD). Lower amounts detected in pancreatic juice are probably due to proteolysis during sample collection.