Figure 1. 17-b-estradiol plasma levels in ovariectomized rats (V) and rats treated with different doses of 17-b- estradiol (E, EX10, EX100). Data are expressed as mean ± SEM. Only significant differences are shown. Significant interday comparison: * day 16 vs. days 6 and 11; ** day 6 vs. days 11 and 16