Figure 3. Adhesion of PanC1, MiaPaCa and BxPC3 to MECs. Prior to tumor cell adhesion, the MECs were pre-incubated for 12 hours with 10 ng/mL IL-1beta and/or for 1 hour with anti-E-selectin (E-sel), anti- ICAM-1 (ICAM-1), both anti-E-selectin and anti- ICAM-1 (E-sel+ICAM-1) or anti-VCAM-1 (VCAM- 1). Mean±SD values are shown. Generally, n=6 samples were evaluated for each experiment. (One-way ANOVA). Black P values refer to the comparisons with values observed without added antibodies (either untreated MAC or IL-1beta pre-incubated MECs): the simple contrast was applied. Red P values refer to the comparisons between untreated MAC and IL-1beta pre-incubated MEC; repeated contrast was applied.