Figure 3. Quantitation of GABAA receptor π subunit expression relative to beta-actin. Expression of the receptor π subunit mRNA was measured by RT-PCR in pancreatic ducts without malignancies (Duct, n=6) and pancreatic adenocarcinomas (Tumor, n=12) and defined relative to beta-actin mRNA expression in each tissue. GABAA receptor π subunit mRNA expression levels were significantly elevated in tumors compared to normal pancreatic ducts (*P=0.026).