targeting
Figure 3. Gene targeting of the prepancreatic and prehepatic territories of the mouse endoderm. A-C and D-F. Two series of adjacent sections of the same embryo electroporated at the 8 somite stage and cultured for 24 h. Sections stained with antibodies against GFP and against the epithelial marker E-cadherin (A, D), against the pancreatic marker Pdx-1 (B, E), or against the hepatic marker Prox1 (C, F), showing that GFP was delivered to the prepancreatic region. dpb: dorsal pancreatic bud hb: hepatic bud