Figure 5. a. The TUNEL-positive acinar cells are abundant in the pancreas of the WBN/Kob rat at 12 weeks (left), but there are only a few TUNEL-positive acinar cells in the pancreas of the Wistar rat at 12 weeks (right). b. Time course of apoptotic index in the pancreases of the WBN/Kob rat. The apoptotic index showed two peaks at 12 and 20 weeks. Each point represents the mean±SEM of 6 observations. P values vs. previous time interval