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Figure 4. The effect of camostat mesilate (CA) and TJ-10 (TJ) on TP53INP1 mRNA expression in the WBN/Kob rat. a. A single band of 289 bp was faintly seen in the camostat mesilate and TJ-10-treated groups. The GAPDH mRNA of 452 bp as an internal control was expressed in all pancreatic tissue. b. TP53INP1 mRNA levels were reduced at all ages, especially at 12 weeks, in camostat mesilate (CM) and TJ-10 (TJ) treated WBN/Kob rats compared with the untreated group (U: these data are also reported in Figure 1). Each point represents the meanĀ±SEM of 6 observations. P values between pairs of different groups.