a L-arginine is acting as a secretagogue for the newly generated islets as the level of insulin secreted by the neoislets in response to L-arginine is comparable (P=0.104) to the level of insulin secreted by control islets in response to 16.5 mM glucose.

Table 1: Comparison of insulin secretion levels of control islets (islets from non-diabetic mice) with neoislets against glucose and L-arginine secretagogue response. Quantitative analysis of insulin secretion was done by ELISA. Insulin levels were measured in μIU/mL against a standard curve. Inter-assay variability is less than 5.2%. (Three observations were made for each cell).