Figure 1: Mother explant culture of islets (arrow) from STZ-treated experimental diabetic mouse pancreas giving rise to epithelial-like cells on matrigel coated plates within 24 hours after islet attachment (Figure 1a). Epithelial-like cell monolayer containing intra islet precursor cells formed in the culture with well-defined serum-free medium (Figure 1b). Intra islet precursor cells of epithelial-like cell sheet stained with epithelial cell specific marker CK-19; CK immunostaining was examined by confocal microscopy (green fluorescence, Figure 1c).