rats
Figure 4: The incidence of diabetes in BB rats treated with whole spleen cells transduced with MSCVneo.IL- 4 retroviral vector. Twelve prediabetic 3-4 wk old BB rats were injected with 5-10x106 MSCVneo.IL-4 transduced cells (Treatment) and 12 rats were treated with control cells containing MSCVneo control vector (Control). Blood glucose measurements (two successive daily plasma glucose measurements greater than 11.1 mmol/L) were used to assess diabetes. Using Kaplan Meier survival analysis with log rank test no significant difference (P=0.150) was found between rats treated with transduced cells and the control group.