American Journal of Advanced Drug Delivery Open Access
ISSN: 2321-547X
Journal h-index: 22
Journal CiteScore: 9.36
Journal Impact Factor: 5.76
Average acceptance to publication time (5-7 days)
Average article processing time (30-45 days)
Less than 5 volumes 30 days
8 - 9 volumes 40 days
10 and more volumes 45 days
Abstract
Synthesis and Antimicrobial Screening of Some Azetidine Derivatives
Rakesh Patel and Anil Bhandari
New series of N-(3-chloro-2-oxo-4-substituted-azetidine-1-yl) isonicotinamide derivatives were synthesized by the reaction of Schiff base with 2-chloroacetic acid. Synthesized compounds were evaluated for their Anti-bacterial activity against staphylococcus aureus and Echerichia coli, Antifungal activity against C Albicans and Anti-tubercular activity against mycobacterium tuberculosis. Synthesized compounds show significant activity against bacterial, fungal and mycobacterium strains. Their structures were established on the basis of elemental analysis, IR, 1H NMR and Mass Spectral data.
