Anna Caterina Milanetto, Loredana Iaria, Rita Alaggio, Sergio Pedrazzoli, Claudio Pasquali
Context In the last years, cystic pancreatic lesions are often detected when clinically silent, because of the wider use ofdiagnostic imaging techniques. First described by Othman in 2007, “squamoid cyst of pancreatic ducts” represents a cysticdilation of ducts, lined by non-keratinized squamous epithelium. We report the first case of squamoid cyst of pancreaticducts in Italy. Case report A 68-year-old woman presented a cystic lesion (4 cm) of the pancreatic tail as incidental finding atMRI. It had a thickened wall, no internal septa and no communication with the Wirsung duct were detected. A CT scanshowed a lamellar calcification on its posterior wall. A 18F-FDG-PET was negative. Blood tests were normal, including CEAand CA 19-9. We performed a spleen-preserving distal pancreatectomy. Histology showed a unilocular cyst, with serous fluid and a fibrous wall, with multilayered epithelium without cytological atypias. Immunohistochemistry showed CK 7 positive and CK 5 negative. The patient is still alive and without disease after 42 months of follow-up. Conclusions In the English literature only seven cases resected for this cyst type have been reported. No preoperative test can achieve a definitive diagnosis, so surgical resection remains the treatment of choice in order to exclude malignancy. However, afterintraoperative frozen section, a limited pancreatic resection can be performed.
