Background: In recent years, the relevance of vitamin D receptor (VDR) gene restriction fragment length polymorphisms and
BMI has been investigated by a great number of studies. It has been hypothesized that VDR polymorphisms may influence
the bone mass. However, studies investigating the associations between specific VDR polymorphisms and bone mass often
show controversial results. We have now performed a systematic review of the literature to analyse the relevance of VDR
polymorphisms for bone mass.