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Abstract

Next-generation sequencing and its applications

NGS is new innovation for DNA and RNA sequencing and variation/transformation recognition. This innovation consolidates the benefits of interesting sequencing sciences, distinctive sequencing networks, and bioinformatics technology. Such a blend permits a massive parallel sequencing of different lengths of DNA or RNA arrangements or even whole genome within a moderately short period of timeframe. It is a progressive sequencing innovation after Sanger sequencing.

NGS includes a several significant steps in sequencing. For instance, DNA NGS includes DNA fragmentation, library preparation, massive parallel sequencing, bioinformatics analysis, and variation/ mutation annotation and interpretation.


Author(s): Neha H

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