European Journal of Experimental Biology Open Access

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Abstract

Anti-inflammatory and antimicrobial activities of the extracts of Eclipta alba Leaves

Muthu Kumaran Peraman, P. Ramalingam, and Bapatla JNN Sai

The aqueous and ethanolic extracts of the leaves of Eclipta alba (Astraceae) were evaluated for their anti-inflammatory activity using carrageenan-induced rat paw oedema method in albino rats. The antimicrobial activity was also been performed against the bacteria Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and the fungi Candida albicans and Aspergillus niger by agar plate disc diffusion method. The results indicated that the ethanolic extracts (200mg/kg) have shown significant anti-inflammatory activity with p value of 0.005 and however, both of the extracts were exhibited moderate antibacterial and antifungal activity against the test organism.