Pathogenesis of influenza

Influenza virus is introduced into the airways by aerosol or by contact with saliva or other respiratory secretions from an infected individual, it binds to and replicates in epithelial cells.of both the upper and lower respiratory tract. Viral replication combined with the immune response to infection lead to destruction and loss of the epithelial cells the respiratory mucosa. Cough and weakness may persist for up to 2 weeks after infection. Influenza enters the host through the airways.


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