Effects of Mutation

If a mutation occurs in a non-coding region then it will have little or no effect. Even if it occurs in a coding region - for example a region that contains codes for amino acids used to build vital proteins - it might not have an adverse effect. For example, a substitution that turns CUU into CUA in RNA molecule will have no effect, since both are codes for the same amino acid (leucine).

Classification of types

By effect on structure:

  1. Substitution Mutation
  2. Deletion Mutation
  3. Insertion Mutation
  4. Chromosomal Translocation

By effect on function:

  1. Loss-of-function mutations
  2. Gain-of-function mutations
  3. Dominant negative mutations
 

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