Combination of Genetic and Environmental Problems

Some congenital abnormalities may occur if there is a genetic tendency for the condition combined with exposure to certain environmental influences within the womb during critical stages of the pregnancy (e.g. Spina bifida and cleft lip and palate).

Taking folate supplements prior to conception and during pregnancy decreases the risk of neural tube defects. However, there is also a genetic influence to this type of congenital anomaly.


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