There is a tremendous need in Cardiology to focusing along the translational direction to fill the gap between experimental data obtained in the Laboratory and the clinical application (or applicability). The driving force should be the need to manage resources yet increasing the potential for human use of evidence obtained through basic research. A forum whereby Clinicians sensitive to the great potential of basic studies would help. However, such a specific forum actually does not exist and represents the major aim of this Journal. Translational Cardiology is subdivided into 8 sections: 1) Translational Cardiac Rhythmology; 2) Translational Cardiac Contractile Biology; 3) Translational Vascular Biology; 4) Translational Blood Stream Biology; 5) Translational Neurocardiology; 6) Translational Cardiovascular Genetics and Regenerative Biology; 7) Translational Cardiac Engineering and Imaging and 8) Translational Cardiovascular Technologies. Each section is leaded by 2 Co-Editors, one of Clinical and the other of Experimental derivation and/or orientation. A reputed panel of Experts has accepted to be actively involved in this new adventure. We then look forward to receiving high quality submissions from the scientific world, which will at the end show the real success of our initiative.