Ph.D, Professor, Department of Avian Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Ziyue Road 518, Shanghai, 200241, P.R. China.
|EDUCATION : PhD, Nangyang Technological University, Singapore. BSc,East China Normal University, China. PROFESSIONAL EXPERIENCE: Professor, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, China Research Fellow, School of Biological Sciences, Nangyang Technological University, Singapore. Research Fellow, Institute of Molecular and Cell Biology, A*STAR, Singapore.|
|The general interest of my lab is to understand the epidemiology and biology of avian viruses. In particular we wish to understand the epidemicity, the cross species transmission, tissue tropism, pathogenesis, innate immune response to virus infection. My current research focuses characterization of the entry and uncoating mechanisms, ER stress response, virus-induced cell death, virus escape from innate immune response. This research has employed the infectious bronchitis virus (IBV) and the Newcastle disease virus (NDV) as model systems and uses a multidisciplinary experimental approach which employs molecular biology, imaging technology and proteomics. It is hoped that a detailed understanding of the intimate relationship between these individual viruses and the host-cell during infection will lead to the anti-viral drug and vaccine development.|