|Dr. Cynthia Haseltine
Associate Professor, School of Molecular Biosciences Biotechnology/Life Sciences, Washington State University, USA.
|Dr. Haseltine became interested in the biology of extremophiles early in her graduate education at the University of Nebraska ? Lincoln where she focused primarily on central metabolism and regulation of gene expression in Sulfolobus solfataricus. She expanded her exploration of how these organisms survive in their environmental niche by shifting focus to DNA repair and genome stability during her postdoctoral appointment. In her own laboratory at Washington State University, Dr. Haseltine currently employs molecular, biochemical, genetic, and cellular approaches to understand how cells can grow and thrive in nearly boiling acid.|
|My laboratory uses the hyperthermophilic acidophile Sulfolobus solfataricus as a model system to study recombination, repair, and genome stability mechanisms. This archaeal microbe thrives in hot, acidic, terrestrial volcanic hot springs found across the world and shares attributes with members of both the bacterial and eukaryotic domains of life. By virtue of its evolutionary position, study of its simpler biological pathways for nucleic acid handling will form a platform for understanding more complex related mechanisms in eukaryotes.|
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