Gopalakrishnan V

Gopalakrishnan V

Professor, Faculty of Pharmacology,University of Saskatchewan

 
Biography

Professor and Head: Department of Pharmacology,  College of Medicine, University of Saskatchewan

Academic Credentials: B.Sc., Chemistry, University of Madras, India,M.Sc., University of Madras, India, Ph.D., University of Madras, India, (JIPMER)

Email: [email protected], Ph:3069666220

 
Research Interest

Cellular and Subcellular Basis for the Vascular and Cardiac Actions of Peptides (arginine vasopressin, angiotensin II, endothelin and ghrelin). Studies involve characterization of Ca2+ signal transduction events regulated by peptides using: i) functional measurement of changes in tension responses of cardiac and vascular tissues, perfused vascular bed preparations (ii) receptor binding and receptor expression studies using primary cultures of neonatal rat cardiomyocytes, minimally passaged cultured rat vascular smooth muscle (VSM) cells and endothelial cells (EC), iii) agonist(s)-evoked changes in effector systems (measurement of IP3, cAMP, cGMP, cysteinyl leukotrienes and [Ca2+]i levels and protein kinase C activity), (iv) quantification of [Ca2+]i, changes in single cardiomyocyte, VSM cells and EC using imaging technique. The major focus is to examine the role of these peptides in both normal as well as experimental models of hypertension and diabetes mellitus

Global Experts in the subject
A Anton Smith A Bhargavi A K Dinda
ANURAG KHATKAR Abbas Akhgari Abhishek Bhatt
Abubaker Siddiq Adigwe Obi Peter Adinarayana Gorajana
Agrawal Neeraj Ahmad A Ahmad Ayaz
Ahmad Sayeed Ahmad Wasim Aijaz A Sheikh
Ait Hamadouche N Ajmera Ankit Ali Ismail Al Gareeb
Ali Mirza Asif Alireza Jahangiri Alka Tomar
Alvin Jose Manonmani Alvin Josemanonmani Amanpreet Kaur
Ambati Brahma Reddy Amit Mittal Amit Sahu
Amita Vats Amul Mishra Anand Chaurasia
AneeshTP Anil Kumar Ch Anilkumar J Shinde
Anindya Bagchi Anitha Nandagopal Anitha Roy
Ankit Ajmera Ankur Saxena Ankush Gupta
Ansari Sh Anup Kumar Roy Anupkumar Roy
Anurag Khatkar Apurva Deshpande Apurva Laxmikant Deulker
Armita Azarpanah Arun Kumar Sinha Arvind Setia
Asaduzzaman Muhammad Ashish Sancoalcar Ashok Kumar P
Ashwlayan Vrish Dhwaj Avari Jg Avijit Choudhury
Avinash Gudigennavar B Jayanthi B Samyuktha Rani
Balakrishnan N BalamuralidharaV Balasubramaniam A
Bansal M Barik B B Basavaraj K Nanjwade
Behera Bc Behzad Sharif Makhmalzadeh Bele D
Bendgude Ravindra D Bhagwat Durgacharan A Dr. Fabio Fumagalli