American Journal of Advanced Drug Delivery Open Access
ISSN: 2321-547X
Journal h-index: 22
Journal CiteScore: 9.36
Journal Impact Factor: 5.76
Average acceptance to publication time (5-7 days)
Average article processing time (30-45 days)
Less than 5 volumes 30 days
8 - 9 volumes 40 days
10 and more volumes 45 days
Abstract
Synthesis of Substituted 7-Methyl-2,8-Dihydropyrazolo[1,5-�?Ž�?±][1,3,5]-Triazine Derivatives for Anti-Inflammatory and Anti- Microbial Screening
Niraj V. Patel and Dr. Dhrubo Jyoti Sen
A series of condensed pyrazolo and triazine derivatives have been synthesized to their physical property melting point, % yield, retention factor (Rf) have been evaluated. Structure is confirmed by UV, IR, NMR and Mass. All synthesized compounds are screened for two biological activities (Anti-inflammatory and Anti-microbial). Anti-inflammatory activity has been carried out by rat paw edema method while anti-microbial activity has been carried out by filter paper disc method. MIC (minimum inhibitory concentration) for antimicrobial screening has been carried out by tube dilution method.
