Abstract

Synthesis and biological evaluation of carbamate and sulfonamide derivatives of carvedilol

The modified structures of Carvedilol as their carbamates and sulfonamides were synthesized by the reaction of Cavedilol with different Chloroformates/sulfonylchlorides in the presence of triethylamine at reflux temperature in THF. The newly synthesized compounds were characterized by IR, NMR (1H & 13C), LCMS and C, H, N elemental analysis. All the title compounds were screened for their antimicrobial activity.


Author(s): Sana Venkata Lakshmi Reddya, Sk. Thaslim Bashaa, Kondapalli Nareshb and Chamarthi Naga Raju

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