Abstract

Synthesis and Bioassay of α-aminophosphonates

An efficient and direct protocol is described for the preparation of α-amino phosphonates derivatives by employing a three component one-pot condensation reaction of aldehyde, amine and dialkyl phosphonates under solvent-free conditions by using microwave irradiation. The green procedure offers advantages such as shorter reaction time, simple work-up and high yields


Author(s): Y. Haranadha Reddy, B. Siva kumar, G. Chandrasekhar Reddy, E. Dadapeer and K. Subramanyam Reddy

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