Abstract

Sodium perchlorate catalysed synthesis of 1,5-benzodiazepines in an aqueous media

Sodium perchlorate was found to be an efficient agent for the preparation of 2,3-Dihydro-1H-1,5-benzodiazepine derivatives by the condensation of o-phylenediamine and various ketones in the presence of stoichiometric amount of NaClO4 in an aqueous media.


Author(s): Sangita S. Makone and Dattatray B. Vyawahare

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