Biomarkers Journal Open Access

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Abstract

Proteomic Study of Aqueous Humor in Neovascular Glaucoma after anti-VEGF therapy

Liangliang Zhao, Junyi Li, Fujie Yuan, Kelin Liu, Ying Wang

Proteomics is a large-scale study of proteins, which affects our understanding of genetic function to a large extent since we usher in genomic period. The most important breakthrough in proteomics is generally acknowledged as the identification of proteins via mass spectrometry, which excels over simple protein display supported by traditional technology in both accuracy and efficiency. Recently, mass spectrometry has been utilized to analyze differentially expressed proteins between pathological state and normal individual. Hence, changes of aqueous humor proteomics in neovascular glaucoma (NVG) patients before and after anti-VEGF therapy was briefly reviewed.