Reach Us +441414719275
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Preliminary Phytochemical Studies and Evaluation of Antidiabetic Activity of Stem Bark of Acacia senegal (L.) Willd. in Alloxan Induced Diabetic Albino Rats

The aim of present study was to investigate the potential of stem bark of Acacia senegal (L.) Willd for antidiabetic activity in alloxan induced diabetic albino rats. Phytochemical studies showed the presence of flavonoids in ethyl acetate extract. Antidiabetic activity of stem bark of this plant was evaluated by measuring blood glucose levels and serum biochemical parameters after dosing with ethyl acetate extract. Blood samples were collected from overnight fasted diabetic rats on 0, 5, 10 and 15 days of treatment to determine glucose levels. On day 16, blood samples were collected to estimate biochemical parameters. In diabetic rats, both the doses (200 mg/kg and 400 mg/kg) of ethyl acetate extract were found to be significantly (P<0.05) active in comparison to control and favourable changes in biochemical parameters were also observed. It can be concluded from this study that the ethyl acetate extract of stem bark of A. senegal possess significant antidiabetic activity.


Author(s): Shikha Batra, Nikhil Batra and Badri Prakash Nagori.

Abstract | PDF

Share this  Facebook  Twitter  LinkedIn  Google+
Flyer image

Abstracted/Indexed in

  • Chemical Abstracts Service (CAS)
  • Google Scholar
  • Sherpa Romeo
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • Open Academic Journals Index (OAJI)
  • Directory of Research Journal Indexing (DRJI)
  • Publons
  • Scientific Journal Impact Factor
  • International Committee of Medical Journal Editors (ICMJE)
  • Secret Search Engine Labs