The microbiological investigation of selected organs of Clarias gariepinus exposed to effluents from a soap and detergent industry, in Ilorin was carried out. The microbiological analyses of the selected organs (gills, and skin) showed that the index of the microbial load is in order of 106, indicating that the effluent is highly populated with fungi and bacteria. The results showed that the metal components of the industrial effluents bioaccumulated in the organs of fish, this phenomenon was thought to have brought about the enhanced growth of microorganisms in the organs. The probability of being exposed to non point pollution was considered. Notable microorganisms in the organs of the fish include the following; Proteus vulgaris, Bacillus Sp, Streptococcus faecium, Eschericia coli.