A healthy lifestyle always comprises of good food habits. To immunize various lifestyle disorders, consumers switched to the functional food that helps is fulfil the nutritional requirement of the human body additionally protects from multiple diseases. Probiotic microorganisms that are generally known as the friendly microorganism play an essential role in this regard. It establishes a symbiotic association with the human host. This mini-review includes the name of various probiotic microorganisms and their focus on human health benefits as well as in reducing the risk associated with pathogenic diseases.