Abstract

Evaluation of Antibody Response to Newcastle Disease Vaccination in Chickens in Some Commercial Farms-Ii Two Local Government Areas in Lagos State, Nigeria

Newcastle disease is of great economic importance causing devastating losses among both intensive, extensive and backyard poultries that provides lifeline to many poor people across the developing world. Despite the availability of ND vaccines, vaccination failure suffices in most poultry farms. This study evaluated antibody response following vaccination against Newcastle disease. A total of five hundred and thirty four sera were collected and one hundred and thirty three were negative. The sera were tested for NDV antibody using Haemagglutinationinhibition test in two Local Government Areas (LGAs): Badagry and Ojo of Lagos state, Nigeria. A total of two hundred and thirty seven sera were tested in Badagry, and seventy six were negative with mean Ab titre of 5.04 ± 3.26, mode of = 3log2 of 32.1 while one hundred and sixty one were positive with 4log2 of 38.4. Farm visited were mostly into layers production with provisions for brooding chicks and raising growers. Risk factors identified were rodent infestation, unmanned gate, lizard infestation and lack of PPE. Ojo had a total of two hundred and ninety seven sera tested with one hundred and fourteen were negative with mean Ab titre of 4.36 ± 3.36 mode of = 3log2 of 38.4% while one hundred and eighty three were positive with mode of = 4log2 of 61.9. The immunity in different age group varies within the 2 LGAs. The risk factors identified were rodent infestation, lizard infestation, lack of PPE and risky visitors. In conclusion more than thirty percent of chickens within Badagry and Ojo LGAs in Lagos State of Nigeria vaccinated against NDV were not protected from the disease.


Author(s): Ambali HM, Nwoha RIO and Abdu PA

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