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Abstract

Clinical Evaluation of Justicia tranquebariensis L. In the Management of Bronchial Asthma

Objective: The aim of the study was to assess the therapeutic efficacy of Justicia tranquebariensis (Thavasu murungai) in bronchial asthma.
Materials and Methods: 40 asthmatics were enrolled for the clinical trial. The patients were selected according to the patient subjective assessment scale, objective parameters and WHO GINA guideline. The patients with severe diseases such as AIDS, Malignancy, TB, Renal and CVS disorders were excluded from the study. This open labeled study was conducted at Government Siddha Medical College Hospital, Chennai-106. All the patients were administered 30 ml leaf juice of Justicia tranquebariensis for the period of 3 months. Clinical trial usually focuses on asthma control as measured by pulmonary function test (FEV1, FVC, PEFR, Breath holding time and FVR), symptom scores and medication requirement. The study infers improvement on subjective and objective parameters of bronchial asthma. During the trial period, 4 patients were discontinued from the study due to need for parenteral and inhalation therapy. 36 patients were completed the study. Results: There was a significant improvement in all parameters compared at each follow up visit. Based on the result out of 36 cases 29 had marked response, 5 had moderate response and only 2 cases had fair response. No side effects have been observed during the study period.
Conclusion: Thus we concluded that Justicia tranquebariensis (Thavasu murungai) is effective for the treatment of bronchial asthma.


Author(s): V. Velpandian, S. Elangovan, L. Naansi Agnes and M. Mohamed Musthafa

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