Sumesh Raj, Baiju S J, Rajesh Vijayan and G.V. Rajan
Background: Type 2 diabetes mellitus (T2DM) influences bone metabolism, but the relation of T2DM with bone mineral density (BMD) remains inconsistent across studies. The objective of this study was to estimate the difference in BMD (g/cm2) between diabetic and non-diabetic populations, and to investigate potential underlying mechanisms.
Materials and methods: The association between T2DM and BMD measured by dual energy X-ray absorptiometry was evaluated, including both healthy controls and subjects with T2DM.
Results: Analysis showed that BMD in diabetics was significantly higher than non-diabetic at various sites. The differences in forearm BMD were not significantly different between diabetics and non-diabetics. Analysis showed similar results in both sexes. Also, it was seen that younger age, male sex, higher body mass index and higher HbA1C were positively associated with higher BMD levels in diabetic patients.
Conclusion: Patients with T2DM have higher BMD levels when compared to non diabetics.
