American Journal of Advanced Drug Delivery Open Access

  • ISSN: 2321-547X
  • Journal h-index: 22
  • Journal CiteScore: 9.36
  • Journal Impact Factor: 5.76
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days

Abstract

An Efficient One Pot Synthesis of Pyrazolo [3,4-b] pyrido[1,2-a] pyrimidine and its Antimicrobial Evaluation

Sambhaji P. Vartale, Nagesh D. Kalyankar &Nilesh K. Halikar

Pyrazolo pyrimido pyrimidine (4a-j) were prepared by the reaction of compound 3-cyano-4-imino-7-methyl-2-(methylthio)-4Hpyrido [1,2-a] pyrimidine (3) with hydrazine hydrate, phenyl hydrazine, 2-hydrazino benzothiazole & 6-substuited hydrazine benzothiazole in N,N-dimethyl formamide (DMF) and catalytic amount of anhydrous potassium carbonate. All these newly synthesized compounds were characterized by elemental analysis and spectral data